case studies of stem cell transplantation in india

Stem Cell Treatment Case Studies

Spino Cerebellar Ataxia - Patient ID- B241

The patient is a basketball player and a health care professional. His problem began 5 years ago when it became increasingly difficult to play. Soon he developed intermittent diplopia (double vision) as well. He progressively also had problems with his balance, coordination, slurring of speech and excessive fatigue. Different neurologists gave varied diagnosis that was inconclusive and he was provisionally considered as a case of SCA. Read More

Spino cerebellar Ataxia (SCA) condition Treatment - Patient ID- 11UIN1011

The patient, 7 years ago developed progressive loss of balance (ataxic gait), weakness in the limbs and slurring of speech. Since last 3 years, the neurologist diagnosed the condition as SCAconfirmed after gene testing with a background of family history. He is wheel chair bound at present.Read More

Spino Cerebellar Ataxia – Patient ID – B330

She was diagnosed as SCA a few years ago. It began when she experienced difficulty in walking, balancing and climbing stairs together with slurring of speech, choking sensation while taking food and loss of bladder control. Read More

Cerebral Palsy Neuro-Developmental Disorder Treatment - Patient ID- I393

Patient had this neurodevelopmental disorder since infancy. She also had paralysis in all four limbs which was gradual in onset and kept increasing. She had a history of seizures as she was also afflicted with mental retardation. Read More

Cerebral Palsy - Patient ID- I568

Patient had this neurodevelopmental disorder since birth. According to his history, he did not cry at birth and was kept on ventilator support. Gradually, mental retardation and seizure disorder were noticed, which included paralysis of the whole body. Read More

Cerebral Palsy with Microcephaly and Visual Impairment – Patient ID – 1309

The patient had developed this neuro developmental disorder at birth. He was born on the 27th week of pregnancy and kept on ventilator. He stayed in neonatal ICU for 2 months. He had no communication skills and had delayed developmental mile stones with almost diminished overall gross motor functions. There was also a history of seizures and drooling of saliva. Read More

Spastic Cerebral Palsy - Patient ID - 1396

Patient had this neurodevelopmental disorder since birth. He was born preterm (at 27-28 weeks) and did not cry at birth. He was kept on ventilator support and was discharged from the NICU after a month. Subsequently, he was diagnosed with cerebral palsy based on the MRI and clinical features of spasticity and limb weakness. Read More

Spastic Cerebral Palsy - Patient ID - 1199

Mesenchymal Stem Cells derived from Wharton’s Jelly of Human Umbilical cord. He received 6 injections of stem cells, 3 through Intravenous route in a dose of 1million cells/kg body weight and 3 injections of adequate cells through intrathecal route. Read More

Multiple Sclerosis - Patient ID- B129

The patient, a qualified radiologist, was diagnosed with this condition in 2003 when he experienced weakness in his finger flexors of the right hand. The symptoms gradually progressed to stiffness and weakness in the left side of his body. Subsequently, the lower limbs were also involved. He was bed ridden with spasticity and weakness in almost all the muscle Groups. Read More

DMD - Patient ID- 11UIN1129

Patient had gradual weakness in all four limbs since the age of 5. At the time of admission in February 2012, he was completely bedridden with feeds through gastrostomy, including using BiPAP at night because of breathing difficulties. Read More

Duchenne Muscular Dystrophy - Patient ID- I315

The patient was fine till the year 2009. Thereafter, he started to have progressive weakness in his limb muscles and was diagnosed as DMD by a neurologist. He is wheel‐chair bound since June 2012. Read More

Limb Girdle Muscular Dystrophy - Patient ID- 11BKC1037

There was marked weakness in the muscles of all his limbs and in the power of shoulder, scapula and trunk muscles. He experienced difficulty in climbing stairs, walking and changing positions from sitting to standing position. He fatigued easily and had diminished stamina for daily activities. Activities such as combing hair, brushing teeth and eating with hands were difficult. However, he had no problem in writing. Read More

Optic Nerver Atrophy - Patient ID- 12BKC1292

On the morning of 10th July 2009 when the patient woke up he noticed a small white spot at the center of his vision and by the evening, he could not see anything and was totally blind. With all kinds of treatment there was little improvement and the patient was diagnosed with optic nerve atrophy untreatable by any conventional method. Read More

ROP - Patient ID- I389

Patient was born prematurely at 26 weeks and weighed only 750 grams. She was in the incubator for 2 months. Later she was diagnosed with blindness in one eye and had 5% sight in the other eye. She had retinal detachment as well as macular degeneration, both of which were corrected through surgery. She also had corrective surgery for 2% atrial septal defect. Read More

Optic Nerve Atrophy – Patient ID – 1519

The patient had tried all available conventional treatments in the best of eye hospitals in his country and elsewhere. The patient was diagnosed with progressive atrophy of the optic nerve (Leber’s) (85% of the optic nerve damage with expanding central scotoma). He had gradual loss of vision in both eyes (Rt eye more left eye). Since last year there was loss of central vision. He had no history of trauma, drug history or family history. Read More

Optic Nerve Atrophy – Patient ID –M125

The patient is a case of residual neurological deficit following severe form of brain injury & optic atrophy as a result of a road traffic accident in 2008. Initially, he was in coma for many months and his chances of significant recovery were meagre as per the doctors at the time. Read More

Optic Nerve Atrophy – Patient ID – 1353

Patient had suddenly lost vision of her right eye in 2006. She gradually was losing vision in her left eye since 2009. She was diagnosed with optic neuritis due to an unknown cause which subsequently progressed to optic atrophy thereby making the patient permanent blind. Read More

Retinopathy of Prematurity with Hypothyroidism - Patient ID - B354

The patient was born premature several weeks before full term. She was later diagnosed as visually impaired due to ROP since birth, the left eye more involved than the right eye. Microcornia was present in both eyes and microphthalmos was present in right eye. Read More

Spinal Cord Injury - Patient ID- B429

Patient had tried all available conventional treatments in the best of spinal injury hospitals in his country and found no improvements. He tried new emerging treatments like stem cells twice at Beike and felt benefited. Subsequently the parents approached us for repeat treatment. Read More

Spinal Cord Injury - Patient ID- I243

Patient sustained spinal cord injury in the cervical region while exercising in a gymnasium. He was operated upon and the injury stabilised. Later in 2009, he underwent stem cell treatment in China to improve his quality of life and noticed improvement in the muscle power of his lower limbs. There were no side effects of the stem cell therapy. Read More

Spinal Cord Injury - Patient ID- W292

The patient was diagnosed in 2006 with reducible atlanto -axial dislocation with myelomalacic spinal cord as a result of trauma 14 years ago. Spinal cord decompression surgery was done and spine was stabilized. This was unsuccessful and the patient was completely paralyzed neck down.After natural recovery, the power in all muscles improved to grade 4. Read More

Spinal Cord Injury – Patient ID – I192

The patient met with a road traffic accident in 2008, and suffered complete spinal cord injury. He was paralyzed from chest down with no movement of legs and partial movement of arms. Read More

Spinal Cord Injury – Patient ID – 1394

The patient had sudden onset paralysis in lower part of body including both his lower limbs in 2010 which was diagnosed as Ischemic myelitis due to erratic absorption of penicillin causing blocking of the artery to spinal cord. Read More

Osteoarthritis – Patient ID – S527

He progressively experienced pain during walking and bending, stiffness in the hip and knees. He could climb stairs only one step at a time with a lot of pain. Descending stairs was very painful. He suffered from shooting pain quite frequently. Read More

Motor Neuron Disease (Amyotrophic Lateral Sclerosis - ALS) – Patient ID B544

Patient first started to have problems in January 2011 when she had pain in her right wrist followed by weakness and slurring of speech, which turned out to beALS when her diagnosis was confirmed in May 2012. Read More

Spinal Muscular Atrophy - Patient ID - B641 & B642

Both twins were born prematurely through IVF procedure at 6 and half months of gestation. The twins were delivered by caesarian section. The third baby was a still birth. B641 had respiratory distress syndrome and intra ventricular hemorrhage at birth and was revived in ICU, Subsequently all milestones were delayed and he could never stand with support. B642 had similar events but with less severity. There was no intra ventricular hemorrhage and he was able to achieve milestones of standing with support but could never walk independently. Both could roll, bear weight on their arms and lift their heads to a comfortable position. When they were 18 to 24 months of age both started to lose power and movements in their limbs and began to deteriorate. They were diagnosed with SMA (Spinal Muscular Atrophy) Type II, completely unknown to their parents. Both boys needed more support with sitting and B642 could no longer stand even with support. However, they continued to have normal mental and speech development. Read More

Spinal Muscular Atrophy - Patient ID - B335

The patient had an adult onset of SMA which was provisionally diagnosed after excluding all other diseases with similar clinical presentation. His problem began around 2 years ago when his speed while walking had gradually slowed down. Subsequently, after 6 months, his right limb became stiff and his feet came out of slippers. He developed difficulty in walking on uneven ground. Gradually his left lower limb also got involved. Read More

Spino Muscular Atrophy - Patient ID - 11BKC1147

Patient had gradual weakness in all four limbs since the age of 2. At the time of admission in April 2012, he had difficulty while getting up from the squatting position or getting up from a chair and while climbing stairs or lifting any weight. His parents had tried all available conventional treatments in India’s best neurology hospitals but saw no improvement in his condition. Read More