Stem Cell Treatment FAQ’s
Stem cell therapy is a form of regenerative medicine that involves the transplantation of stem cells through one or more injections to replace diseased or injured cells. Stem cells are undifferentiated cells that have the ability to help perform a variety of regenerative functions.
What types of stem cells does Unistem provide?
Unistem provides only Adult Stem Cells in its therapies. We do not provide embryonic/fetal stem cells. Adult Stem Cells can be taken from many sources including umbilical cord blood, bone marrow, or fat tissue. Currently, Unistem’s stem cells are principally sourced from umbilical cord tissue and autologous mesenchymal stem cells from the bone marrow.
What is the role of Unistem group in research?
The backbone of Unistem is the groundbreaking research and the standardized protocols established by ourassociates. Peer reviewed papers have been published in both International and Indian medical journals and is listed in the Research Hub. Unistem is undertaking pre-clinical trials for safety and efficacy of in-house processed umbilical cord derived mesenchymal stem cells in collaboration with National Institute of Immunology, Delhi.
Are therapies using Unistem’s stem cells safe?
Toxicity studies of its umbilical cord derived mesenchymal stem cells to establish safety of these cells for human use by various routes has been successfully completed at a government approved laboratory, Intox Pvt. Ltd, Pune. Unistem, in its first year of operating has provided therapy to over 50 patients at Delhi since 2012 with no significant adverse effects that have been related to stem cell transplants. Since 2005, more than 15,000 patients internationally have been treated with Beike's stem cell technology. Our medical department doctors review in-depth medical information provided by patients and it is only after this review that patients may be accepted for therapy. A practice of strict adherence to the inclusion and exclusion criteria for stem cell therapy is followed by the Unistem medical team.
What quality control standards does Unistem have in place?
Unistem has established rigorous quality control standards for stem cell processing and release for therapy. The world-class stem cell processing facility is compliant with GLP, GTP, GDP and GCP. The laboratory strictly adheres to guidelines of DCGI, ICMR, DBT, ISO-9001, USFDA, AABB and FACT-NETCORD. The umbilical cord blood stem cell processing facility operates with the license as approved by DCGI. Beike has been accredited by the American Association of Blood Banks (AABB, 2010). It has been awarded the ISO9001:2008 certification to its laboratories.
Is HLA matching and immunosuppression necessary to avoid graft versus host disease (GVHD)?
There is a common assumption that any transplantation of cells requires HLA matching and immunosuppression. In regards to transplantation of umbilical cord tissue stem cells, research has clearly shown that these are not needed to prevent GVHD. Umbilical cord tissue stem cells lack well-developed immune cells that could attack the recipient’s body.
What tests are used to screen donated umbilical cord blood and tissue prior to processing?
The maternal blood undergoes numerous testing, including tests for hepatitis B & C, HIV, syphilis, malaria, CMV and HTLV, besides ABO and Rh blood grouping. Additionally, the donated cord blood stem cells will be tested for HLA typing and genetic screening for haemoglobinopathies.
Where is the therapy provided?
The therapy is provided both for domestic and international patients at the Unistem affiliated hospital presently located in Delhi NCR. For more information, please visit our Location Information Hub or click on the hospital photos to see more.
How long is the therapy period?
Generally, one therapy cycle depends on the patient’s condition and is designed with the following considerations:
- Appropriate time to observe and ensure patient safety.
- Sufficient stem cells as per dosage criteria to be administered.
- Enough time for a comprehensive rehabilitation program including acupuncture and physiotherapy, as the case maybe to help ensure the maximum efficacy of the therapy.
We require that patients are kept under our supervision in a controlled environment. A private room is provided to each patient in the hospital. It is important to remember that stem cell therapy is a medical procedure that has to be provided in a hospital setting.
Is it possible for me to visit the hospital during the decision making process?
We know that many patients and care givers are interested in visiting the hospital. Our affiliated hospital can provide patients with a tour. If you are interested in visiting the hospital, please let us know and we can provide you with all the necessary instructions for arranging a visit. Please note that the visit must be arranged and confirmed in advance and the visit can only be arranged after the patient’s full medical information has been reviewed by our doctors.
Will Stem Cell Therapy improve my condition?
Research has shown cord mesenchymal stem cell therapy improves the quality of life of the patient, however, this improvement may vary from patient to patient and these changes may be seen while the patient is on therapy or after the completion of the therapy.
Why do Unistem therapy protocols include rehabilitation?
During a typical theray cycle, rehabilitation is provided. Rehabilitation helps to potentiate stem cells throughout the body. The physiotherapy regime followed is specifically to analyze the patient’s progress in neurological disorders.
What else can I do to get the most out of my stem cell therapy?
It is important that you arrive for therapy as healthy as possible and that you avoid fevers, colds, infections, and injuries. Stem cells naturally migrate to the injured or sick areas of the body and any secondary infections could lead to a decreased quantity of stem cells available to relieve your primary neurological or vascular condition.
There are some simple steps you can follow both during and after your therapy to protect and nurture new cells. These include avoiding sugar-rich foods and avoiding tobacco and alcohol products for six months, eating neuron-protective foods that are high in omega-3, utilizing supplements such as folic acid and turmeric extract, avoiding and minimizing stress, and maintaining a moderate (but not extreme) exercise program. In combination, these steps may help protect and provide a healthy environment for newly developed cells.
Does UCB or UCMSC stem cell therapy cause Cancer?
It is important to note that there is generally very little to no concern by informed or unbiased scientists about cord blood, cord mesenchymal or bone marrow derived stem cells, unlike embryonic/fetal stem cells, causing cancer or tumors. None of our patients treated have developed cancer due to the therapy. Researchers are currently finding ways to use umbilical cord derived stem cells to cure tumors and treat cancer patients.
What are the most important steps needed to finalize acceptance for therapy?
Please review all information provided to you by us.
Complete the Initial Medical Information Form. Additionally, please send any necessary MRIs, CTs, etc. Our technical team is available for any assistance needed.
Upon submission, our medical department will review the medical information and in certain cases they might request more information and medical documentation if required.
After a review of the medical information has been completed, the medical department will provide a final determination on therapy suitability.
If patient is acceptable for therapy, you will be sent the therapy Registration Form. This must be filled out with the proposed dates that the patient wants to arrive for therapy.
Our Clinical Research & Medical Affairs department will coordinate with the hospital staff and confirm a therapy period as close to the desired dates. The therapy details will be communicated thereafter.
For international patients the Travel Request Form submitted, including airline, passport, and visa information, is required at least two weeks before the arrival date. Following registration, we will provide you and your accompanying party with invitation letters. On arrival our service staff will pick you up and drive you to the hospital.