What is motor neuron disease (MND)?

MND is a serious disorder related to nerve cells and damage nervous system, slowly and gradually spine and brain nerves lose functioning. MND is a neurological disorders, neurons are found in the brain and spinal cord. They relay the information delivered by the brain that monitors the muscular action. The motor neuron disease (MND) is a degenerative disease that induces muscles paralysis (limbs, swallowing and breathing). The most common form is amyotrophic lateral sclerosis (ALS). The existing therapies ease patients’ pain but do not cure them.

There are four most common type of Motor neuron disease depending on the pattern of motor neuron involvement.
  • Amyotrophic lateral sclerosis (ALS).
  • Progressive bulbar palsy (PBP).
  • Progressive muscular atrophy (PMA).
  • Primary lateral sclerosis (PLS).

Motor Neurone Disease Early Symptoms

  • Muscle cramps.
  • Feel difficulty while picking up or holding objects.
  • Progressive loss of speech.
  • Tough to climbing stairs.
  • Stumbling due to weakness.

Who is at risk by motor neuron disease affect?

Motor neurone disease (MND) is an uncommon and progressive condition. MND may affect people with all ages, including young and old. MND diagnosis vary from person to person according to their ages.

The treatment is very complex because several cell types should be replaced and signals set-up again. Mesenchymal stem cells (MSC) therapy is available as an alternative therapeutic strategy in improving patient’s condition by regenerating damaged and dead neurons allowing for reduced patient symptoms and slowing down of the disease progression.

Many patients have reported improvements in

  • Activities of daily living e.g. Speech, walking, using hands, swallowing
  • Quality of life index e.g. reduced breathlessness, fatigue, lethargy, pain etc.
  • Slowdown in progression of disease and hence better life expectancy  

Motor Neuron Disease (Amyotrophic Lateral Sclerosis - ALS) – Patient ID B544